Carlisle United have been given odds of 12/5 to end their Rodney Parade hoodoo today.
The Blues have never won at Newport County's current ground in eight visits - drawing three times and losing five.
And bookmakers give the home side the edge this afternoon despite the Exiles' current poor form.
Victory for James Rowberry's hosts is 21/17 with SBK, 6/5 with Betfair and 23/20 with William Hill.
READ MORE: Can the Blues banish their Rodney Parade hoodoo?
An away win for Paul Simpson's side is 12/5 with Coral, 23/10 with Bet365 and 9/4 with 888 Sport.
The draw in south Wales is 12/5.
Omar Bogle, Newport's experienced frontman, is 11/2 favourite to get the first goal this afternoon.
Carlisle top scorer, Kristian Dennis, who has been nursing a hamstring problem this week, is 6/1 for the opener.
Home defender Micky Demetriou, a scorer against the Blues in the past, is 22/1 to score first and 8/1 to find the net at any time in the game.
Other first scorer options for the Blues, meanwhile, include Jack Stretton at 9/1, Owen Moxon at 20/1, Jon Mellish at 25/1 and last weekend's goal hero Callum Guy at 40/1.
Carlisle are 9/1 to pick up a 1-0 victory, 11/2 to draw 1-1 and 42/5 for a 2-0 defeat.
A repeat of last season's 2-2 draw at Rodney Parade is 15/1.
And a 2-1 Carlisle win - the score in United's most recent away win against Newport at their former Somerton Park home in April 1988 - is priced 11/1.
Source: Oddschecker.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here