Carlisle United are 7/2 to complete a league double over Bolton Wanderers and give their survival hopes a much-needed boost.
SkyBet and Coral are among the bookmakers offering those odds for a Blues victory at Brunton Park today.
Paul Simpson's United are 10/3 with William Hill and 16/5 with Bet365 for a win to follow October's memorable victory at the Toughsheet Community Stadium.
Promotion-chasing Bolton are odds-on to reinforce their challenge with a win in Cumbria.
Ian Evatt's side are 3/4 for victory with 888Sport and BoyleSports, and 4/5 with UniBet.
The draw at Brunton Park is 14/5.
The clubs' last meeting saw an inspired Jordan Gibson score a hat-trick for Carlisle.
The midfielder is 16/1 to open the scoring today, and 500/1 for another treble against the Trotters.
Bolton's 18-goal Dion Charles is the 9/2 favourite for the first goal with Victor Adeboyejo 11/2 and Paris Maghoma 13/1.
Ex-Blues man Kyle Dempsey, who is an injury doubt, has odds of 13/1 for the opener with fellow former Carlisle player Jack Iredale 25/1.
For Carlisle, new boy Jack Diamond is 12/1 for the opening goal while Luke Armstrong is 17/2 to make it back-to-back openers, with Dan Butterworth 14/1, Alfie McCalmont 22/1, Jon Mellish 40/1 and former Bolton man Sam Lavelle also 40/1.
Josh Vela is 25/1 to mark his United debut with the opener against his former club.
United have odds of 40/1 to chalk up another 3-1 win against the division's third-placed side.
A 1-0 home win is 11/1 and a 2-1 Blues victory is 14/1.
Bolton are 6/1 to pick up a second 1-0 win in the space of five days after Tuesday's victory over Cheltenham Town.
The visitors are 15/2 to win 2-0 and 14/1 to triumph 3-1.
A repeat of the teams' last meeting at Brunton Park - a 3-3 draw on Boxing Day 2020 - is 80/1.
Carlisle's last win over the Trotters on home soil came back in April 1983...and if you're feeling really confident, you can back a repeat of that day's 5-0 victory at odds of 200/1.
Source: Oddschecker.
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